What causes leptin deficiency?

In the hypothalamus, the binding of leptin to its receptor triggers a series of chemical signals that affect hunger and help produce a feeling of fullness (satiety). LEP gene mutations that cause congenital leptin deficiency lead to an absence of leptin. Congenital leptin deficiency is a rare cause of obesity.

Why is Leptin not a cure for obesity?

Maintenance of weight loss is often unsuccessful because of metabolic adaptations that conserve energy. Studies in rodents suggest that a reduction in leptin level during weight loss signals to the brain to increase feeding and decrease energy expenditure.

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What is the purpose of chest tube water seal?

The middle chamber of a traditional chest drainage system is the water seal . The main purpose of the water seal is to allow air to exit from the pleural space on exhalation and prevent air from entering the pleural cavity or mediastinum on inhalation.

What causes leptin deficiency?

In the hypothalamus, the binding of leptin to its receptor triggers a series of chemical signals that affect hunger and help produce a feeling of fullness (satiety). LEP gene mutations that cause congenital leptin deficiency lead to an absence of leptin. Congenital leptin deficiency is a rare cause of obesity.

Why is Leptin not a cure for obesity?

Maintenance of weight loss is often unsuccessful because of metabolic adaptations that conserve energy. Studies in rodents suggest that a reduction in leptin level during weight loss signals to the brain to increase feeding and decrease energy expenditure.

About Pupi

Check Also

What is the purpose of chest tube water seal?

The middle chamber of a traditional chest drainage system is the water seal . The main purpose of the water seal is to allow air to exit from the pleural space on exhalation and prevent air from entering the pleural cavity or mediastinum on inhalation.

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